Publications 2014

Bannwarth, S. Ebert, M. Lauck, M. Ziener, S. Tomcin, G. Jakob, K. Münnemann, V. Mailänder, A. Musyanovych, K. Landfester
Tailor-Made Nanocontainers for Combined Magnetic-Field-Induced Release and MRI
Macromol. Biosci. 2014, 14, 1205 – 1214
DOI: 10.1002/mabi.201400122

Tomcin, G. Baier, K. Landfester, V. Mailänder
Pharmacokinetics on a microscale: visualizing Cy5-labeled oligonucleotide release from poly(n-butylcyanoacrylate) nanocapsules in cells
International Journal of Nanomedicine 2014, 9, 5471–5489;
DOI: 10.2147/IJN.S70908

Paiphansiri, G. Baier, A. Kreyes, D. Yiamsawas, K. Koynov, A. Musyanovch, K. Landfester
Glutathione-Responsive DNA-Based Nanocontainers Through an “Interfacial Click” Reaction in Inverse Miniemulsion
Macromol. Chem. Phys. 2014, 215, 2457−2462
DOI: 10.1002/macp.201400374

Kristin Mohr*, Sophie S. Müller*, Laura K. Müller, Kristiane Rusitzka, Sabine Gietzen, Holger Frey, and Manfred Schmidt
Evaluation of Multifunctional Liposomes in Human Blood Serum by Light Scattering
November 12, 2014 /in: Langmuir. DOI: 10.1021/la502926e

Ugur Sahin, Katalin Kariok, Özlem Türeci
mRNA-based therapeutics--developing a new class of drugs
2014 Oct;13 / Nat Reviews Drug Discovery
DOI: 10.1038/nrd4278

Anne-Kathrin Barthel, Martin Dass, Melanie Dröge, Jens-Michael Cramer, Daniela Baumann, Markus Urban, Katharina Landfester, Volker Mailänder, Ingo Lieberwirth
Imaging the intracellular degradation of biodegradable polymer nanoparticles
Beilstein J. Nanotechnol. 2014, 5, 1905-1917. published 29 Oct 2014. DOI: doi:10.3762/bjnano.5.201

T. Fritz, M. Hirsch, F. C. Richter, S. S. Müller, A. M. Hofmann, U. Massing, H. Frey, M. Helm.
Click Modification of Multifunctional Liposomes with Hyperbranched Polyether Chains
2014, Biomacromolecules, 15, 2440-2448. DOI: 10.1021/bm5003027

T.V. Demina, O. A. Budkina, G. A. Badun, N. S. Melik-Nubarov, H. Frey, S. S. Müller, J. Nieberle, I. D. Grozdova
Cytotoxicity and Chemosensitizing Activity of Amphiphilic Poly(glycerol)–Poly(alkylene oxide) Block Copolymers. 2014, Biomacromolecules, 15, 2672-2681. DOI: 10.1021/bm500521j

Hofmann, Daniel; Tenzer, Stefan; Bannwarth, Markus B; Messerschmidt, Claudia; Glaser, Simone-Franziska; Schild, Hansjorg; Landfester, Katharina; Mailander, Volker
Mass spectrometry and imaging analysis of nanoparticle-containing vesicles provide a mechanistic insight into cellular trafficking.
ACS nano, Volume:8, Issue:10, Pages:10077-88, DOI:10.1021/nn502754c

Glaffig, B. Palitzsch, S. Hartmann, C. Schüll, L. Nuhn, B. Gerlitzki, E. Schmitt, H. Frey, H.Kunz,
"A Fully Synthetic Glycopeptide Antitumor Vaccine Based on Multiple Antigen Presentation on a Hyperbranched Polymer“
Chem. Eur. J.
201415, 4232-4236

R. Luxenhofer, M. Barz, M. Schillmeier
Quo Vadis Nanomedicine?
Nanomedicine 2014, 9 (14), 2083-2086. doi:10.2217/nnm.14.140

Heller, A. Birke, D. Huesmann, B. Weber, K. Fischer, A. Reske-Kunz, M. Bros, M. Barz.
Introducing PeptoPlexes: Polylysine-block-Polysarcosine Based Polyplexes for Transfection of HEK 293T Cells. Macromol Biosci 2014, 14, 1380–95. DOI: 10.1002/mabi.201400167 (cover page article)

P. Heller, B. Weber, M. Barz.
Synthesis and Sequential Deprotection of Triblock Copolypept(o)ides Using Orthogonal Protective Group Chemistry.
Macromol Rapid Commun 2014, DOI: 10.1002/marc.201400466 (cover page article)

P. Heller, N. Mohr, B. Weber, A. Birke, A. Reske-Kunz, M. Bros, M. Barz.
Directed Interactions of Block Copolypept(o)ides with Mannose-binding Receptors: PeptoMicelles targeted to Cells of the Innate Immune System.
Macromol Biosci 2014, DOI:10.1002/mabi.201400417 (cover page article, highlighted at Materials Views)

Lutz Nuhn, Sabine Gietzen, Kristin Mohr, Karl Fischer, Kazuko Toh, Kanjiro Miyata, Yu Matsumoto, Kazunori Kataoka, Manfred Schmidt, and Rudolf Zentel*
Aggregation Behavior of Cationic Nanohydrogel Particles in Human Blood Serum
Biomacromolecules 15, 1526 -1533 (2014); DOI 10.1021/bm500199h

Nicole Mohr, Matthias Barz*, Romina Forst, Rudolf Zentel*
A Deeper Insight into the Postpolymerization Modification of Pentafluorophenylmetacrylates to Poly-N-(2-hydroxypropyl)-methacrylamide
Macromol. Rapid Commun. 35, 1461–1541 (2014); DOI: 10.1002/marc.201400249

Kristof Tappertzhofen, Monika Bednarczyk, Kaloian Koynov, Matthias Bros, Stephan Grabbe and Rudolf Zentel*
Towards Anticancer Immunotherapeutics: Well-Defined Polymer-Antibody Conjugates for Selective Dendritic Cell Targeting
Macromol. Biosci. 14,14, 1444–1457 (2014); Doi 10.1002/mabi.201400190

Hanno Schieferstein, Annette Kelsch, Achim Reibel, Kaloian Koynov, Matthias Barz, Hans-Georg Buchholz, Nicole Bausbacher, Oliver Thews, Rudolf Zentel*, Tobias L. Ross*
18F-Radiolabeling and Preliminary Evaluation of Folate-pHPMA Conjugates via PET,
Macromol. Biosci. 14, 14, 1396–1405 (2014); DOI 10.1002/mabi.201400200

Lutz Nuhn*, Lydia Braun, Iris Overhoff, Annette Kelsch, David Schaeffel, Kaloian Koynov, Rudolf Zentel*
Degradable Cationic Nanohydrogel Particles for Stimuli-Responsive Release of siRNA
Macromol. Rapid. Commun. in press (2014); DOI: 10.1002/marc.201400458

Lutz Nuhn, Stephanie Tomcin, Kanjiro Miyata, Volker Mailänder, Katharina Landfester, Kazunori Kataoka, Rudolf Zentel*
Size-Dependent Knockdown Potential of siRNA-Loaded Cationic Nanohydrogel Particles
Biomacromolecules, 15, 4111-4121 (2014); DOI: 10.1021/bm501148y (2014)

Marco Lelle, Stefanie U. Frick, Kerstin Steinbrink and Kalina Peneva
Novel cleavable cell-penetrating peptide– drug conjugates: synthesis and characterization
J. Peptide Sci. (2014), 20, 323-333; DOI 10.1002/psc.2617

Jasmin Bühler, Sabine Gietzen, Anika Reuter, Cinja Kappel, Karl Fischer, Sandra Decker, David Schäffel, Kaloian Koynov, Matthias Bros, Ingrid Tubbe, Stephan Grabbe, and Manfred Schmidt
Selective Uptake of Cylindrical Poly(2-Oxazoline) Brush-AntiDEC205 Antibody-OVA Antigen Conjugates into DEC-Positive Dendritic Cells and Subsequent T-Cell Activation
ChemPubSoc: DOI: 10.1002/chem.201403942

Kristin Mohr, Maria Sommer, Grit Baier, Susanne Schöttler, Patricia Okwieka, Stefan Tenzer, Katharina Landfester*, Volker Mailänder, Manfred Schmidt and Ralf Georg Meyer
Aggregation Behavior of Polystyrene-Nanoparticles in Human Blood Serum and its Impact on the in vivo Distribution in Mice
J Nanomed Nanotechnol 2014, 5:2; DOI: 10.4172/2157-7439.1000193

Kerstin Malzahn, Filippo Marsico, Kaloian Koynov, Katharina Landfester, Clemens K. Weiss, and Frederik R. Wurm
Selective Interfacial Olefin Cross Metathesis for the Preparation of Hollow Nanocapsules
ACS Macro Letters: DOI: 10.1021/mz400578e | ACS Macro Lett. 2014, 3, 40−43

Anna Musyanovych, Katharina Landfester
Polymer Micro- and Nanocapsules as Biological Carriers with Multifunctional Properties
Marcomolecular Bioscience: DOI: 10.1002/mabi.201300551

Martin Weilbächer, Mareli Allmeroth, Mirjam Hemmelmann, Sandra Ritz, Volker Mailänder, Tobias Bopp, Matthias Barz, Rudolf Zentel* and Christian Becker∗
"Interaction of N-(2-Hydroxypropyl)Methacrylamide Based Homo, Random and Block Copolymers with Primary Immune Cells"
J. Biomed. Nanotechnol. 10, 81 -91 (2014); Doi:10.1166/jbn.2014.1693

D. Huesmann, A. Birke, K. Klinker, S. Türk, H.J. Räder, M. Barz
"Revisiting Secondary Structures in NCA Polymerization: Influences on the Analysis of Protected Polylysines"
Macromolecules, 2014, DOI: 10.1021/ma5000392

A. Birke, D. Huesmann, A. Kelsch, M. Weilbacher, J. Xie, M. Bros, T. Bopp, C. Becker, K. Landfester, M. Barz
Polypeptoid-block-Polypeptide copolymers: Synthesis, Characterization and Application of Amphiphilic
"Block Copolypeptides in Drug Formulations and Miniemulsion Techniques"
Biomacromolecules, 2014, DOI: 10.1021/bm401542z

D. Hofmann, C. Messerschmidt, M. B. Bannwarth, K. Landfester, V. Mailänder
"Drug delivery without nanoparticle uptake: delivery by a kiss-and-run mechanism on the cell membrane."
Chem. Commun. 2014, 50, 1369-71; DOI: 10.1039/c3cc48130a
http://www.rsc.org/chemistryworld/2013/12/kiss-and-run-drug-delivery

C. Loos, T. Syrovets, A. Musyanovych, V. Mailänder, K. Landfester, T. Simmet
“Amino-functionalized nanoparticles as inhibitors of mTOR and inducers of cell cycle arrest in leukemia cells”
Biomaterials. 2014, 35, 1944-53; DOI: 10.1016/j.biomaterials.2013.11.056