Nadine Leber, Rudolf Zentel.
“Improved SiRNA Loading of Cationic Nanohydrogel Particles by Variation of
Cross-Linking Density”
Macromol. Chem. Phys. 2020, 221.
DOI: 10.1002/macp.201900298.
Zimmer N., Kim E., Sprang B., Leukel P., Khafaji F., Ringel F., Sommer C., Tuettenberg J, Tuettenberg A.
“GARP as an immune regulatory molecule in the tumormicroenvironment of glioblastoma multiforme”
Int J Mol Sci. (2019). 20, 3676.
DOI: 10.3390/ijms20153676.
Kleszczyński K, Kim TK, Bilska B, Sarna M, Mokrzynski K, Stegemann A, Pyza E, Reiter RJ, Steinbrink K, Böhm M, Slominski AT.
“Melatonin exerts oncostatic capacity and decreases melanogenesis in human MNT-1 melanoma cells”
J Pineal Res. (2019) Nov;67(4):e12610.
DOI: 10.1111/jpi.12610.
Gore E, Bigaeva E, Oldenburger A, Kim YO, Rippmann JF, Schuppan D, Boersema M,
Olinga P.
“PI3K inhibition reduces murine and human liver fibrogenesis in precision-cut liver slices”
Biochem Pharmacol. (2019) Nov; 169:113633.
DOI: 10.1016/j.bcp.2019.113633.
Bigaeva E, Gore E, Mutsaers HAM, Oosterhuis D, Kim YO, Schuppan D, Bank RA,
Boersema M, Olinga P.
“Exploring organ-specific features of fibrogenesis using murine precision-cut tissue slices”
Biochim Biophys Acta Mol Basis Dis. 2020 Jan
1; 1866(1):165582.
DOI: 10.1016/j.bbadis.2019.165582.
Judith Stickdorn, Lutz Nuhn
“Reactive ester derived nanogels for cancer immunotherapy”
European Polymer Journal (2019).
DOI: 10.1016/j.eurpolymj.2020.109481.
Ruben Re Coen, Lutz Nuhn, Chamani Perera, Maria Arista Romero, Martijn Risseeuw, Alec Freyn, Raffael Nachbagauer, Lorenzo Albertazzi, Serge Van Calenbergh, David A. Spiegel, Blake R. Peterson, Bruno G. De Geest
“A Synthetic Rhamnose Glycopolymer as Cell Surface Receptor for Endogenous Antibody Recruitment”
Biomacromolecules (2019).
DOI: 10.1021/acs.biomac.9b01483.
Ma BC, Caire da Silva L, Jo SM, Wurm FR, Bannwarth MB, Zhang KAI, Sundmacher K, Landfester K.
“Polymer-Based Module for NAD+ Regeneration with Visible Light”
Chembiochem. (2019) Oct 15;20(20):2593-2596.
DOI: 10.1002/cbic.201900093.
Champanhac C, Simon J, Landfester K, Mailänder V.
“Timing of Heparin Addition to the Biomolecular Corona Influences the Cellular Uptake of Nanocarriers”
Biomacromolecules. (2019) Oct 14;20(10):3724-3732.
DOI: 10.1021/acs.biomac.9b00777.
Guindani C, Frey ML, Simon J, Koynov K, Schultze J, Ferreira SRS, Araújo PHH, de Oliveira D, Wurm FR, Mailänder V, Landfester K
“Covalently Binding of Bovine Serum Albumin to Unsaturated Poly(Globalide-Co-ε-Caprolactone) Nanoparticles by Thiol-Ene Reactions”
Macromol Biosci. (2019) Oct;19(10):e1900145.
DOI: 10.1002/mabi.201900145.
Prozeller D, Morsbach S, Landfester K.
“Isothermal titration calorimetry as a complementary method for investigating nanoparticle-protein interactions”
Nanoscale. (2019) Nov 7;11(41):19265-19273.
DOI: 10.1039/c9nr05790k.
Tabujew I, Willig M, Leber N, Freidel C, Negwer I, Koynov K, Helm M, Landfester K, Zentel R, Peneva K, Mailänder V.
“Overcoming the barrier of CD8+T cells: Two types of nano-sized carriers for siRNA transport”
Acta Biomater. (2019) Dec;100:338-351.
DOI: 10.1016/j.actbio.2019.10.006.
Liu X, Chen SY, Chen Q, Yao X, Gelléri M, Ritz S, Kumar S, Cremer C, Landfester K, Müllen K, Parekh SH, Narita A, Bonn M
“Nanographenes: Ultrastable, Switchable, and Bright Probes for Super-Resolution Microscopy”
eCollection 2019. Review Angew Chem Int Ed Engl. 2020 Jan 2;59(1):496-502.
DOI: 10.1002/anie.201909220.
Simon J, Bauer KN, Langhanki J, Opatz T, Mailänder V, Landfester K, Wurm FR
“Noncovalent Targeting of Nanocarriers to Immune Cells with Polyphosphoester-Based Surfactants in Human Blood Plasma”
Adv Sci (Weinh). (2019) Oct 4;6(22):1901199.
DOI: 10.1002/advs.201901199.
van der Meel R, Sulheim E, Shi Y, Kiessling F, Mulder WJM, Lammers T.
“Smart cancer nanomedicine”
Nat Nanotechnol. (2019) Nov;14(11):1007-1017.
DOI: 10.1038/s41565-019-0567-y.
Saeed M, Gao J, Shi Y, Lammers T, Yu H.
“Engineering Nanoparticles to Reprogram the Tumor Immune Microenvironment for Improved Cancer Immunotherapy”
Theranostics. (2019) Oct 17;9(26):7981-8000.
DOI: 10.7150/thno.37568
C.M. Berač, L. Zengerling, D. Straßburger, R. Otter, M. Urschbach, P. Besenius
“Evaluation of Charge-Regulated Supramolecular Copolymerization to Tune the Time-Scale for Oxidative Disassembly of ß-Sheet Comonomers”
Macromol. Rapid Commun. (2019), 1900476 Invited contribution to '100 years of polymer research' special issue.
DOI: 10.1002/marc.201900476
Bleher S, Buck J, Muhl C, Sieber S, Barnert S, Witzigmann D, Huwyler J, Barz M, Süss R.
“Poly (Sarcosine) Surface Modification Imparts Stealth‐Like Properties to Liposomes”
Small 15 (50), 1904716.
DOI: 10.1002/smll.201904716
AM Alkilany, L Zhu, H Weller, A Mews, W Parak, M Barz, N Feliu
“Ligand density on nanoparticles: A parameter with critical impact on nanomedicine”
Adv Drug Deliv Rev. 2019 Mar 15;143:22-36.
DOI: 10.1016/j.addr.2019.05.010
Siemer S, Westmeier D, Barz M, Eckrich J, Wünsch D, Seckert C, Thyssen C, Schilling O, Hasenberg M, Pang C, Docter D, Knauer SK, Stauber RH, Strieth S
“Biomolecule-corona formation confers resistance of bacteria to nanoparticle-induced killing: Implications for the design of improved nanoantibiotics”
Biomaterials 192, 551-559.
DOI:10.1016/j.biomaterials.2018.11.028
Chaojian Chen, Katrin Wunderlich, Debashish Mukherji, Kaloian Koynov, Astrid Johanna Heck, Marco Raabe, Matthias Barz, George Fytas, Kurt Kremer, David Yuen Wah Ng, and Tanja Weil
“Precision Anisotropic Brush Polymers by Sequence Controlled Chemistry”
Journal of the American Chemical Society (Cover Page).
DOI: 10.1021/jacs.9b10491
S Mantha, S Qi, M Barz, F Schmid
“How ill-defined constituents produce well-defined nanoparticles: Effect of polymer dispersity on the uniformity of copolymeric micelles”
Physical Review Materials 3 (2), 026002.
DOI: 10.1103/PhysRevMaterials.3.026002
T Schafer, C Muhl, M Barz, F Schmid, G Settanni
“Interactions Between Blood Proteins and Nanoparticles Investigated Using Molecular Dynamics Simulations”
High Performance Computing in Science and Engineering'18. p. 63-74
Pannwitt S, Slama K, Depoix F, Helm M, Schneider D.
“Against expectations: Unassisted RNA adsorption onto negatively charged lipid bilayers”
Langmuir. 2019 Oct 18
DOI: 10.1021/acs.langmuir.9b02830 [Epub ahead of print]
Tabujew I, Willig M, Leber N, Freidel C, Negwer I, Koynov K, Helm M, Landfester K, Zentel R, Peneva K, Mailänder V.
“Overcoming the Barrier of CD8+ T Cells: Two types of Nano-Sized Carriers for siRNA Transport”
Acta Biomater. 2019 Oct 3. pii: S1742-7061(19)30673-7.
DOI: 10.1016/j.actbio.2019.10.006 [Epub ahead of print]
Die Nano-Bio-Grenzfläche: Analyse der Proteinkorona als Schlüssel für die biomedizinische Anwendung von Nanocarriern
GIT-Laborfachzeitschrift (2019)
K. Landfester
“Einführung in die Bio- und Medizinphysik In “Vielfältige Physik - Wissenschaftlerinnen schreiben über ihre Forschung“ D. Duchardt, A.B. Bossmann, A.C. Denz (Hrsg.)”
Springer (2019), Weinheim, p. 265 – 271.
B. Iyisan, K. Landfester
“Polymeric Nanoparticles” in "Biological Responses to Nanoscale Particles: Molecular and Cellular Aspects and Methodological Approaches”
Springer Nature, Heidelberg p. 52 – 84
B. Iyisan, K. Landfester
“Modular Approach for the Design of Smart Polymeric Nanocapsules ”
Macromol. Rapid Commun. 40, Art. No. 1800577
DOI: 10.1002/marc.201800577
D. Prozeller, J. Pereira, J. Simon, V. Mailänder, S. Morsbach, K. Landfester
“Prevention of Dominant IgG Adsorption on Nanocarriers in IgG-Enriched Blood Plasma by Clusterin Precoating”
Adv. Sci. 6, Art. No. 1802199
DOI: 10.1021/acs.biomac.9b00539
A.K. Danner, S. Schöttler, E. Alexandrino, S. Hammer, K. Landfester, V. Mailänder, S. Morsbach, H. Frey, F.R. Wurm
“Phosphonylation Controls the Protein Corona of Multifunctional Polyglycerol-Modified Nanocarriers”
Macromol. Biosci. 19, Art. No. 1800468
DOI: 10.1002/mabi.201800468
C. Weber, M. Voigt, J. Simon, A.K. Danner, H. Frey, V. Mailänder, M. Helm, S. Morsbach, K. Landfester
“Functionalization of Liposomes with Hydrophilic Polymers Results in Macrophage Uptake Independent of the Protein Corona”
Biomacromolecules 20, 2989-2999
DOI: 10.1021/acs.biomac.9b00539
C. Weber, S. Morsbach, K. Landfester
“Possibilities and Limitations of Different Separation Techniques for the Analysis of the Protein Corona”
Angew. Chem. Intern. Ed. 10.1002/anie.201902323
DOI: 10.1002/anie.201902323
R.M. Visalakshan, M.N. MacGregor, S. Sasidharan, A. Ghazaryan, A.M. Mierczynska-Vasilev, S. Morsbach, V. Mailänder, K. Landfester, J.D. Hayball, K. Vasilev
“Biomaterial Surface Hydrophobicity-Mediated Serum Protein Adsorption and Immune Responses”
ACS Appl. Mater. Interf. 11, 27615-27623
DOI: 10.1021/acsami.9b09900
Pektor S, Schlöder J, Klasen B, Bausbacher N, Wagner DC, Schreckenberger M, Grabbe S, Jonuleit H, Miederer M.
“Using immuno-PET imaging to monitor kinetics of T cell-mediated inflammation and treatment efficiency in a humanized mouse model for GvHD”
Eur J Nucl Med Mol Imaging Aug 31
DOI: 10.1007/s00259-019-04507-0
Renner K, Bruss C, Schnell A, Koehl G, Becker HM, Fante M, Menevse AN, Kauer N, Blazquez R, Hacker L, Decking SM, Bohn T, Faerber S, Evert K, Aigle L, Amslinger S, Landa M, Krijgsman O, Rozeman EA, Brummer C, Siska PJ, Singer K, Pektor S, Miederer M, Peter K, Gottfried E, Herr W, Marchiq I, Pouyssegur J, Roush WR, Ong S, Warren S, Pukrop T, Beckhove P, Lang SA, Bopp T, Blank CU, Cleveland JL, Oefner PJ, Dettmer K, Selby M, Kreutz M.
“Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy”
Cell Rep. Oct 1;29(1):135-150.e9
DOI: 10.1016/j.celrep.2019.08.068
Stergiou N, Nagel J, Pektor S, Heimes AS, Jäkel J, Brenner W, Schmidt M, Miederer M, Kunz H, Roesch F, Schmitt E.
“Evaluation of a novel monoclonal antibody against tumor-associated MUC1 for diagnosis and prognosis of breast cancer”
Int J Med Sci. Aug 14;16(9):1188-1198
DOI: 10.7150/ijms.35452. eCollection 2019
Jana De Vrieze, Benoit Louage, Kim Deswarte, Zifu Zhong, Ruben De Coen, Simon Van Herck, Lutz Nuhn, Camilla Kaas Frich, Alexander N. Zelikin, Stefan Lienenklaus, Niek N. Sanders, Bart N. Lambrecht, Sunil A. David, Bruno G. De Geest
“Potent lymphatic translocation and spatial control over innate immune activation by polymer-lipid amphiphile conjugates of small molecule TLR7/8 agonists”
Angewandte Chemie International Edition 2019, 1900120
DOI: 10.1002/anie.20190568
B. Steinborn, P. Hirschle, M. Höhn, T. Bauer, M. Barz, S. Wuttke, E. Wagner, U. Lächelt
“Core-Shell Functionalized Zirconium-Pemetrexed Coordination Nanoparticles as Carriers with a High Drug Content ”
Adv Therapeutics 2019, 1900120
DOI: 10.1002/adtp.201900120
D.M. Loy, P.M. Klein, R. Krzysztoń, U. Lächelt, J.O. Rädler, E. Wagner
“A microfluidic approach for sequential assembly of siRNA polyplexes with a defined structure – activity relationship ”
PeerJ Materials Science 2019, 1-37
DOI: 10.7717/peerj-matsci.1
L. Peng, E. Wagner
“Polymeric Carriers for Nucleic Acid Delivery: Current Designs and Future Directions ”
Biomacromolecules 2019, 20, 3613-3626
DOI: 10.1021/acs.biomac.9b00999
Stefan Kramer, Jens Langhanki, Matthias Krumb, Till Opatz, Matthias Bros, and Rudolf Zentel
“HPMA-Based Nanocarriers for Effective Immune System Stimulation ”
Org. Macromol. Biosci. 2019, 19, 1800481
DOI: 10.1002/mabi.201800481
Ana de la Fuente, Stefan Kramer, Nicole Mohr, Stefanie Pektor, Benedikt Klasen, Nicole Bausbacher, Matthias Miederer, Rudolf Zentel, Frank Rösch
“68Ga-, 111In-oxine: a novel strategy of in situ radiolabeling of HPMA-based micelles”
Org. Am J Nucl Med Mol Imaging 2019, 9(1), 67–83
Nadine Leber, Leonard Kaps, Aiting Yang, Misbah Aslam, Mariacristina Giardino, Sebastian Rosigkeit, Asmaa Mostafa, Lutz Nuhn, Detlef Schuppan, Rudolf Zentel
“α-Mannosyl-Functionalized Cationic Nanohydrogel Particles for Targeted Gene Knockdown in Immunosuppressive Macrophages”
Org. Macromolecular Bioscience 2019, 19, 1900162
DOI: 10.1002/mabi.201900162
Ruben De Coen, Lutz Nuhn, Bruno G. de Geest
“Engineering mannosylated nanogels with membrane-disrupting properties”
Org. Polymer Chemistry 2019, 10, 4297-4304
DOI: 10.1039/c9py00492k
Ghazaryan, K. Landfester, V. Mailänder
“Protein deglycosylation can drastically affect the cellular uptake”
Org. Nanoscale 2019, 11, 10727-10737
DOI: 10.1039/C8NR08305C
R. Otter, P. Besenius
“Supramolecular Assembly of Functional Peptide-Polymer Conjugates”
Org. Biomol. Chem. 2019, 17, 6719-6734
DOI: 10.1039/c9ob01191a
A M Alkilany, L Zhu, H Weller, A Mews, W Parak, M Barz, N Feliu.
“Ligand Density on Nanoparticles: A Parameter with Critical Impact on Nanomedicine”
Adv. Drug Deliv. Rev. 2019
DOI: 10.1016/j.addr.2019.05.010
O Schäfer, D Schollmeyer, A Birke, R Holm, K Johann, C Muhl, C Seidl, M. Barz
“Investigation of α-amino acid N-carboxyanhydrides by X-ray diffraction for controlled ring-opening polymerization”
Tetrahedron Letters 2019, 60 (3), 272-275
DOI: DOI: 10.1016/j.tetlet.2018.12.028
Zimpel, A.; Al Danaf, N.; Steinborn, B.; Kuhn, J.; Höhn, M.; Bauer, T.; Hirschle, P.; Schrimpf, W.; Engelke, H.; Wagner, E.; Barz, M.; Lamb, D. C.; Lächelt, U.; Wuttke, S. “Coordinative Binding of Polymers to Metal–Organic Framework Nanoparticles for Control of Interactions at the Biointerface”
ACS Nano 2019, 13 (4), 3884–3895
DOI: 10.1021/acsnano.8b06287
Q Sun, M Barz, BG De Geest, M Diken, WE Hennink, F Kiessling, Twan Lammers, Yang Shi
“Nanomedicine and macroscale materials in immuno-oncology”
Chemical Society Reviews 2019, 48 (1), 351-381
DOI: 10.1039/C8CS00473K
S. Mantha, S. Qi, M. Barz, F. Schmid
“How ill-defined constituents produce well-defined nanoparticles: Effect of polymer dispersity on the uniformity of copolymeric micelles”
Physical Review Materials 2019, 3, 2, 026002
DOI: 10.1103/PhysRevMaterials.3.026002
Hansel C, Erschfeld S, Baues M, Lammers T, Weiskirchen R, Trautwein C, Kroy DC, Drescher HK.
„The Inhibitory T Cell Receptors PD1 and 2B4 Are Differentially Regulated on CD4 and CD8 T Cells in a Mouse Model of Non-alcoholic Steatohepatitis”
Front Pharmacol. 2019, 10, 244.
DOI: 10.3389/fphar.2019.00244
Sun Q, Baues M, Klinkhammer BM, Ehling J, Djudjaj S, Drude NI, Daniel C, Amann K, Kramann R, Kim H, Saez-Rodriguez J, Weiskirchen R, Onthank DC, Botnar RM, Kiessling F, Floege J, Lammers T, Boor P.
“Elastin imaging enables noninvasive staging and treatment monitoring of kidney fibrosis”
Sci Transl Med. 2019, 11, 486.
DOI: 10.1126/scitranslmed.aat4865
Ergen C, Niemietz PM, Heymann F, Baues M, Gremse F, Pola R, van Bloois L, Storm G, Kiessling F, Trautwein C, Luedde T, Lammers T, Tacke F.
“Liver fibrosis affects the targeting properties of drug delivery systems to macrophage subsets in vivo”
Biomaterials. 2019, 206, 49-60.
DOI: 10.1016/j.biomaterials.2019.03.025
Sadeghi N, Kok RJ, Bos C, Zandvliet M, Geerts WJC, Storm G, Moonen CTW, Lammers T, Deckers R.
“Hyperthermia-triggered release of hypoxic cell radiosensitizers from temperature-sensitive liposomes improves radiotherapy efficacy in vitro”
Nanotechnology. 2019,30, 26, 264001
DOI: 10.1088/1361-6528/ab0ce6
Mossanen JC, Kohlhepp M, Wehr A, Krenkel O, Liepelt A, Roeth AA, Möckel D, Heymann F, Lammers T, Gassler N, Hermann J, Jankowski J, Neumann UP, Luedde T, Trautwein C, Tacke F.
“CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4+ T-Cell-Dependent Control of Senescence”
Gastroenterology. 2019, 156, 6, 1877-1889
DOI: 10.1053/j.gastro.2019.01.247
Bartneck M, Schrammen PL, Möckel D, Govaere O, Liepelt A, Krenkel O, Ergen C, McCain MV, Eulberg D, Luedde T, Trautwein C, Kiessling F, Reeves H, Lammers T, Tacke F.
“The CCR2+ Macrophage Subset Promotes Pathogenic Angiogenesis for Tumor Vascularization in Fibrotic Livers”
Cell Mol Gastroenterol Hepatol. 2019, 7, 2, 371-390.
DOI: 10.1016/j.jcmgh.2018.10.007
Heinrich MA, Bansal R, Lammers T, Zhang YS, Michel Schiffelers R, Prakash J.
“3D-Bioprinted Mini-Brain: A Glioblastoma Model to Study Cellular Interactions and Therapeutics”
Adv Mater. 2019, 31, 14, e1806590
DOI: 10.1002/adma.201806590
Dadfar SM, Roemhild K, Drude NI, von Stillfried S, Knüchel R, Kiessling F, Lammers T.
“Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications”
Adv Drug Deliv Rev. 2019, 138, 302-325
DOI: 10.1016/j.addr.2019.01.005
J. Simon, S. Christmann, V. Mailänder, F.R. Wurm, K. Landfester
“Protein Corona Mediated Stealth Properties of Biocompatible Carbohydrate-based Nanocarriers”
Isr. J. Chem. 2018, 58, 1363 – 1372
DOI: 10.1002/ijch.201800166
S. Han, M. Raabe, L. Hodgson, J. Mantell, P. Verkade, T. Lasser, K. Landfester, T. Weil, I. Lieberwirth
“High-Contrast Imaging of Nanodiamonds in Cells by Energy Filtered and Correlative Light-Electron Microscopy: Toward a Quantitative Nanoparticle-Cell Analysis”
Nanoletters 2019, 19, 2178-2185
DOI: 10.1021/acs.nanolett.9b00752